From Seattle Grace to Grey Sloan Memorial, test your knowledge of the most iconic medical drama on television.
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Grey's Anatomy is one of the longest-running primetime medical dramas in television history, created by Shonda Rhimes and premiering on ABC on March 27, 2005. Set in the fictional Grey Sloan Memorial Hospital in Seattle — originally named Seattle Grace Hospital — the show follows a group of surgical interns and attendings navigating the impossible demands of modern medicine. With over 20 seasons and a devoted global fanbase, it has become a cultural landmark, redefining the medical drama genre and launching the careers of countless stars.
The show's emotional core has always been its unforgettable characters. The original five interns — Meredith Grey, Cristina Yang, Izzie Stevens, George O'Malley, and Alex Karev — each brought distinct personalities and tragedies that kept audiences hooked for years. Iconic moments like the bomb-in-the-body-cavity crisis, the Season 6 hospital shooting by Gary Clark, and the Season 8 plane crash have left indelible marks on pop culture. The romance between Meredith and Derek Shepherd ("McDreamy"), immortalized by a Post-it note wedding vow, remains one of the most beloved storylines in television history.
Beyond its drama, Grey's Anatomy broke boundaries — from casting, to storytelling, to its fearless exploration of trauma and resilience. Sandra Oh's performance as Cristina Yang earned her a Golden Globe for Best Supporting Actress in 2006, and the show has continued to attract critical acclaim and cultural conversation ever since. Whether you're a casual viewer or a superfan who can name every Harper Avery Award winner, this quiz will challenge everything you think you know about Seattle's most dramatic hospital.